Introduction：
Binding affinity of antibody is one of the key parameter to determine the efficacy and the dose of an antibody drug. At current stage, the methods to improve the binding affinity of antibody are mainly focus on site-mutation, CDR rearrangement, DNA recombinant, etc. With our unique, propriety affinity maturation technology, we are able to quickly spot the key AA site in antibody domain, and increase the binding affinity of the antibody to at least nM.
Competitive Advantageous：
• Random mutation by DNA-shuffling
• Matured Phage display technology platform that assure high quality of affinity maturation service
• Precise affinity evaluation
• Competitive price
Product/ Service details：
|
Product/ Service |
Deliverable |
Turnaround Time (Business day) |
|
DNA shuffing |
ü Antibody sequence and sequencing report ü Top 1-3 of the optimized antibodies ü Full analysis report (PDF) |
6-7 months |
|
Library construction and screening |
||
|
Antibody production and characterization |
Service Flow：
