Introduction：
Recently, more scientists has turned their views to recombinant antibody fragments due to the complexity and high production cost of monoclonal antibodies (mAbs). Recombinant Antibodies such as Single Domain Antibody (sdAb), is a new generation of engineered antibody fragment that consisted of a single monomeric variable antibody domain, which is derived from camelid heavy chain antibodies, and lacking the light chain and CH domain of the heavy chain in conventional Fab region. By comparing to conventional antibody, sdAb has smaller size, better solubility, and higher stability to function, outstanding permeability, lower immunogenicity and simple cost-effective production. All these advantageous features have made it to have a broader range of applications in biotechnology, pharmaceutical, and immuno-therapeutic use. Based on our extensive expertise in sdAb and advanced sdAb discovery technology, we are able to provide our customer a comprehensive one stop solution from antigen production to specific recombinant sdAb expression.
Competitive Advantageous：
• Experienced single domain antibody production team
• Proprietary UniversalAntigenTM immunization technology
• Advanced Phage-display technology platform
• Advanced Yeast-display technology platform (Large library capacity: ~ 109)
• Minimal cost and progressive payment scheme
Product/ Service details：
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Product/ Service |
Deliverable |
Turnaround Time (Business day) |
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Camel immunization (e.g. dromedaries, camels, llamas, and alpacas) |
√ A glycerol stock of sdAb expressing bacteria (TG1) √ Phage-displayed sdAb library √ Top 5 assayed sdAb strain and their corresponding sequences. √ Full report (PDF) |
5 months |
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PBMC isolation and immune library construction |
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Screening of Phage-displayed library |
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Functional assay for sdAb |
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Large scale sdAb expression by yeast, followed by properties identification |
Standard Process：
Consulting Information：
Please contact us by email or telephone for the specific service price and content.
Email: xilinwu@abrevbio.com & bd@abrevbio.com
Phone: 18805158739
